Refer a friend, you both get £50 off.Refer a friend

    Hot Sale! Up To 70% OffView Offers

    Refer a friend, you both get £50 off.Refer a friend

    Hot Sale! Up To 70% OffView Offers

    Thérapie Clinic
    Thérapie Clinic
    PricingReviewsLocationsShop
    • Injectables/
    • Polynucleotides

    Cosmetic Injections

    Polynucleotides
    Polynucleotides

    From

    £195.00

    Need help choosing?

    Meet with one of our expert providers for a free consultation.

    Over 100,000 five star reviews

    Polynucleotides

    Looking to improve your skin quality without adding volume? Polynucleotides are an advanced regenerative injectable treatment that supports your skin's natural repair process, boosting collagen, hydration, and elasticity for a youthful-looking complexion.

    Select what works for you:

    Book an Appointment

    Meet with one of our doctors, pay during your appointment.

    Buy a Package

    Pay per session or buy a bundle and save.

    From£195.00
    Over 100,000 five star reviews
     What Are Polynucleotides?

    Stronger, healthier skin from within

    What Are Polynucleotides?

    Polynucleotides are an advanced regenerative injectable treatment designed to encourage healthier, stronger, and more resilient skin.

    They are derived from purified DNA fragments found in trout sperm. Rather than adding volume, polynucleotides help reduce the appearance of fine lines and rejuvenate the skin, making them an ideal choice for those seeking natural-looking skin renewal.

    Treatment length

    Treatment length

    30 mins

    Results seen

    Results seen

    3-6 months

    Duration of results

    Duration of results

    Long-term

    Session frequency

    Session frequency

    2-3 Bi Weekly

    How Do Polynucleotides Work?

    The purified DNA fragments within polynucleotides stimulate fibroblast activity to support your body's natural production of collagen and elastin, two essential proteins that help maintain firm, smooth, and revitalised skin.

    Unlike dermal fillers, which are designed to restore lost volume, polynucleotides focus on regenerating the skin from within. As collagen and elastin production increases over time, you'll begin to see gradual improvements in skin quality and texture, with gradual improvements developing throughout your treatment course.

    What Can Polynucleotides Treat?

    What Can Polynucleotides Treat?

    Common skin concerns polynucleotides can help improve:

    • Fine lines and wrinkles
    • Skin laxity
    • Dull or tired-looking skin
    • Dehydrated skin
    • Crepey skin
    • Uneven skin texture
    • Acne scarring

    Polynucleotides Under the Eyes

    The delicate skin beneath the eyes is particularly well suited to polynucleotides treatment. By improving hydration, stimulating collagen and elastin production, and enhancing skin quality, the treatment can help reduce the appearance of fine lines, crepey skin, dark circles, puffiness, and tired-looking eyes.

    Who Is Polynucleotides Treatment Suitable For?

    Who Is Polynucleotides Treatment Suitable For?

    Polynucleotide treatment is suitable for people who want to improve skin quality and support natural skin regeneration.

    You are suitable if you:

    • Have experienced thin or damaged skin.
    • Have noticed the early signs of ageing.
    • Are looking for natural skin rejuvenation.
    • Prefer a treatment that doesn't add volume.
    • Are looking for an alternative to fillers.

    What Are the Benefits of Polynucleotides?

    What Are the Benefits of Polynucleotides?

    Polynucleotide injections offer a range of regenerative benefits, including:

    • Improved overall skin quality.
    • Enhanced skin hydration.
    • Support for natural tissue repair.
    • Boosted skin elasticity.
    • Reduced appearance of crepey skin.
    • Rejuvenation of the delicate under-eye area.

    When Will I See Results?

    Visible improvements typically begin to appear around four weeks after your first polynucleotide treatment, with optimal results becoming noticeable around two months after your second session. For best results, we generally recommend a course of three treatments, spaced 2–4 weeks apart, followed by maintenance treatments every six months.

    Our clients see

    Real Results

    Polynucleotides deliver results you can see and feel. Visible improvements start to appear 4 weeks after your first treatment, with optimal results becoming noticeable two months after your second session. We recommend bi-weekly treatments to really benefit from the full effects of the treatment. The protocol typically involves two sessions spaced apart, with long-lasting effects that continue to improve over time.

    After
    After
    Before
    Before

    Some of our

    Areas that can be treated

    Eyes

    Eyes

    Help reduce the appearance of fine lines, dark circles, and puffiness while improving skin quality.

    Face

    Face

    Improve skin texture, hydration, and elasticity while softening the appearance of fine lines.

    Neck

    Neck

    Reduce the appearance of crepey skin for a smoother, more rejuvenated neck.

    Eyes
    1

    Eyes

    Help reduce the appearance of fine lines, dark circles, and puffiness while improving skin quality.

    2

    Face

    Improve skin texture, hydration, and elasticity while softening the appearance of fine lines.

    3

    Neck

    Reduce the appearance of crepey skin for a smoother, more rejuvenated neck.

    Trust Our Experts

    "Cosmetic Injections are an extension of good skincare. They work by relaxing specific muscles of facial expression that are associated with tiredness, stress and aging. The treatment is tailored and bespoke to every individual patient to create a fresher, more youthful look in a very natural and subtle way."

    Dr. Tom Cryan

    Dr. Tom Cryan

    Thérapie Clinic Expert Doctor

    Experience the

    Thérapie Difference

    OthersOther Providers

    Doctor-led treatments

    Specialists vs. generalists

    Europe's No.1 Aesthetic Clinic

    Over 90 clinics across UK, Ireland and US

    Over 100,000 Five Star reviews

    With over 10 million services completed

    Therapie

    You make us look good

    What our clients say

    Polynucleotides FAQs

    Discover more treatments

    You might also like

    Polynucleotides for Hair Loss

    Polynucleotides for Hair Loss

    Dermal Fillers

    Dermal Fillers

    Anti-Wrinkle Injections

    Anti-Wrinkle Injections

    SkinVive

    SkinVive

    Laser Hair Removal for Women

    Laser Hair Removal for Women

    Become an insider

    Be the first to know about specials, deals and new treatments.

    • Explore
    • Injectables
    • Laser Treatments
    • Skin Treatments
    • Body Treatments
    • Shop Products
    • Special Offers
    • Sitemap
    • Customer Care
    • FAQ
    • Refer a Friend
    • Gift Vouchers
    • Privacy
    • Policies
    • Company
    • About
    • Locations
    • Reviews
    • Blog
    • Careers

    Download our app

    Download on App Store
    Download on Play Store

    Payment methods accepted

    • Visa accepted
    • Mastercard accepted
    • ApplePay accepted
    • GooglePay Accepted
    • Klarna Accepted
    • Clearpay Accepted
    © 2026 Valterous Limited. All Rights Reserved.